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Merck

Y0001246

Azathioprine impurity G

European Pharmacopoeia (EP) Reference Standard

동의어(들):

6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purin-2-amine

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C9H8N8O2S
CAS 번호:
Molecular Weight:
292.28
UNSPSC Code:
41116107
NACRES:
NA.24
기술 서비스
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도움 문의


grade

pharmaceutical primary standard

API family

azathioprine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

S(c3[n](cnc3[N+](=O)[O-])C)c1nc(nc2[nH]cnc21)N

InChI

1S/C9H8N8O2S/c1-16-3-13-6(17(18)19)8(16)20-7-4-5(12-2-11-4)14-9(10)15-7/h2-3H,1H3,(H3,10,11,12,14,15)

InChI key

YFTWHEBLORWGNI-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Azathioprine impurity G EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.




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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문



J Liliemark et al.
Therapeutic drug monitoring, 12(4), 339-343 (1990-07-01)
Two specific high-performance liquid chromatography methods for determining plasma concentrations of azathioprine and 6-mercaptopurine after oral administration of azathioprine are presented. It was shown that azathioprine is unstable in the blood samples unless immediately cooled in ice water. The 2-amino
T A Krenitsky et al.
Journal of medicinal chemistry, 32(7), 1471-1475 (1989-07-01)
Azathioprine [Imuran; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine] is a widely used immunosuppressive and antiarthritic drug. For the sake of comparison, the riboside, the 2'-deoxyriboside, and the arabinoside of azathioprine and its 2-amino congener, thiamiprine, were prepared by an enzymatic method. In vitro, the cytotoxicities



국제 무역 품목 번호

SKUGTIN
Y000124604061833818282