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Y0000777

Methylergometrine for system suitability

Name: Methylergometrine for system suitability
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

동의어(들):

Methylergonovine maleate salt, 9,10-Didehydro-N-[(S)-1-(hydroxymethyl)propyl]-6-methylergoline-8β-carboxamide maleate salt, Methergine maleate salt

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₂₀H₂₅N₃O₂ · C₄H₄O₄

CAS 번호:

57432-61-8

Molecular Weight:

455.50

NACRES:

NA.24

PubChem Substance ID:

329831147

UNSPSC Code:

41116107

MDL number:

MFCD00078588

기술 서비스

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도움 문의

속성

grade

pharmaceutical primary standard

API family

methylergometrine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H]\C(=C(/[H])C(O)=O)C(O)=O.[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N[C@@H](CC)CO)c34

InChI

1S/C20H25N3O2.C4H4O4/c1-3-14(11-24)22-20(25)13-7-16-15-5-4-6-17-19(15)12(9-21-17)8-18(16)23(2)10-13;5-3(6)1-2-4(7)8/h4-7,9,13-14,18,21,24H,3,8,10-11H2,1-2H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t13-,14+,18-;/m1./s1

InChI key

NOFOWWRHEPHDCY-DAUURJMHSA-N

Gene Information

human ... DRD1(1812), HTR2B(3357)

설명

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methylergometrine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Dopamine antagonist interacts with serotonergic, dopaminergic and α-adrenergic systems.

Ergot alkaloid which interacts with serotonergic, dopaminergic and α-adrenergic systems. Dopamine antagonist.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301 + H311 + H331,H361

pcodes

P201 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Methylergonovine maleate as a cluster headache prophylactic: a study and review.

L Mueller et al.

Headache, 37(7), 437-442 (1997-07-01)

Methylergonovine maleate (Methergine), an ergot derivative with vasoconstrictive properties, has been cited as an effective treatment for vascular headaches. Few studies are available to support its use in headache management. An uncontrolled pilot study of 20 episodic cluster headache patients

Oral methylergonovine maleate for refractory migraine and cluster headache prevention.

Joel R Saper et al.

Headache, 53(2), 378-381 (2013-02-26)

Methylergometrine: adverse effects in breastfed infants.

Prescrire international, 23(148), 102-102 (2014-05-27)

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SKU	GTIN
Y0000777	04061833804926