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PHR1720

Clomipramine hydrochloride

Name: Clomipramine hydrochloride
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Clomipramine hydrochloride, 3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, Anafranil hydrochloride

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크기 선택

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₉H₂₃ClN₂ · HCl

CAS 번호:

17321-77-6

Molecular Weight:

351.31

NACRES:

NA.24

PubChem Substance ID:

329823573

UNSPSC Code:

41116107

EC Number:

241-344-3

MDL number:

MFCD00069234

기술 서비스

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도움 문의

속성

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. C2360000, traceable to USP 1140427

API family

clomipramine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

Cl.CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13

InChI

1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H

InChI key

WIMWMKZEIBHDTH-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

설명

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Clomipramine hydrochloride is one of the dibenzazepine tricyclic antidepressants that inhibits noradrenalin and serotonin reuptake in central nervous system. It also shows antimuscarinic properties.

Application

Clomipramine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in traditional Chinese medicine and pharmaceutical formulations by analytical and cyclodextrin-modified capillary zone electrophoresis techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC3902 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS08,GHS07,GHS09

signalword

Danger

hcodes

H302,H336,H370,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 1 - STOT SE 3

target_organs

Central nervous system, Central nervous system,Cardiovascular

저장 등급

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

pcodes

P260 - P264 - P271 - P273 - P301 + P312 - P308 + P311

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Multicommutated flow system for the chemiluminometric determination of clomipramine in pharmaceutical preparations.

Marques KL, et al.

Analytica Chimica Acta, 518(1-2), 31-36 (2004)

Method for simultaneous determination of eight cyclic antidepressants by cyclodextrin-modified capillary zone electrophoresis: applications in pharmaceuticals.

Kou HS, et al.

Analytica Chimica Acta, 525(1), 23-30 (2004)

HPLC and GC?MS screening of Chinese proprietary medicine for undeclared therapeutic substances.

Liu SY, et al.

Journal of Pharmaceutical and Biomedical Analysis, 24(5-6), 983-992 (2001)

국제 무역 품목 번호

SKU	GTIN
PHR1720-1G	04061834802006