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Merck

PHR1621

Butoconazole Nitrate

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Butoconazole nitrate, (±)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole mononitrate

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C19H17Cl3N2S · HNO3
CAS 번호:
Molecular Weight:
474.79
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1082300

API family

butoconazole

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

ClC1=C(C(Cl)=CC=C1)SC(CCC2=CC=C(Cl)C=C2)CN3C=CN=C3.O[N+]([O-])=O

InChI

1S/C19H17Cl3N2S.HNO3/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22;2-1(3)4/h1-5,7-8,10-11,13,16H,6,9,12H2;(H,2,3,4)

InChI key

ZHPWRQIPPNZNML-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Butoconazole nitrate is an antifungal agent belonging to the imidazole class, used for the treatment of vaginal candidiasis. Its mode of action includes interruption of synthesis of cellular ergosterol and disruption of cell membrane.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA5291 in the slot below. This is an example certificate only and may not be the lot that you receive.


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wgk

WGK 3

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



시험 성적서(COA)

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문서 라이브러리 방문



The synthesis and antifungal activity of the enantiomers of butoconazole nitrate
Rotstein DM and Walker KAM
Tetrahedron Asymmetry, 4(7), 1521-1526 (1993)



국제 무역 품목 번호

SKUGTIN
PHR1621-1G04061834793090