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PHR1537

Oxytetracycline

Name: Oxytetracycline
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Oxytetracycline dihydrate, OTC

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

크기 선택

보기 변경

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₂₂H₂₄N₂O₉ · 2H₂O

CAS 번호:

6153-64-6

Molecular Weight:

496.46

NACRES:

NA.24

PubChem Substance ID:

329823449

UNSPSC Code:

41116107

EC Number:

201-212-8

MDL number:

MFCD00151234

기술 서비스

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도움 문의

속성

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

USP 1491004, traceable to Ph. Eur. Y0001896

API family

oxytetracycline

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H24N2O9.H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H2/t12-,13-,14+,17+,21-,22+;/m1./s1

InChI key

IBZHEBHGZFICKS-IFLJXUKPSA-N

설명

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Oxytetracycline is a broad-spectrum antibiotic which finds a wide use in veterinary medicine because of its potential to inhibit the protein synthesis in gram-positive and gram-negative bacteria. It can be used on animal species like cattle, sheep, goats and pigs.

Application

Oxytetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrofluorimetry techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Antibiotic produced by Streptomyces rimosus.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC0364 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

GHS08,GHS09

signalword

Warning

hcodes

H361d,H411

pcodes

P202 - P273 - P280 - P308 + P313 - P391 - P405

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

저장 등급

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Spectrophotometric determination of hydrocortisone, nystatin and oxytetracycline in synthetic and pharmaceutical preparations based on various univariate and multivariate methods.

Gallego JML and Arroyo JP

Analytica Chimica Acta, 460(1), 85-97 (2002)

Quantitative analysis for oxytetracycline in medicated premixes and feeds by second-derivative synchronous spectrofluorimetry.

Fernandez-Gonzalez R, et al.

Analytica Chimica Acta, 455(1), 143-148 (2002)

C18 columns for the simultaneous determination of oxytetracycline and its related substances by reversed-phase high performance liquid chromatography and UV detection.

Smyrniotakis CG and Archontaki HA

Journal of Pharmaceutical and Biomedical Analysis, 43(2), 506-514 (2007)

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국제 무역 품목 번호

SKU	GTIN
PHR1537-1G	04061835237869