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Merck

PHR1123

Isopropyl myristate

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS 번호:
Molecular Weight:
270.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-751-4
Beilstein/REAXYS Number:
1781127
MDL number:
eCl@ss:
39022421
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. I0750000, traceable to USP 1350400

API family

isopropyl myristate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

General description

Isopropyl myristate is an ester of isopropyl alcohol myristic acid. It is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It also finds applications as a flavoring agent in the food industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7001 in the slot below. This is an example certificate only and may not be the lot that you receive.


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저장 등급

10 - Combustible liquids

wgk

awg

flash_point_f

>302.0 °F

flash_point_c

> 150 °C



시험 성적서(COA)

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문서 라이브러리 방문



CRC Handbook of Food, Drug, and Cosmetic Excipients (1992)
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and



국제 무역 품목 번호

SKUGTIN
PHR1123-1G04061835233175