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Merck

H3149

Heparin sodium salt from porcine intestinal mucosa

Grade I-A, ≥180 USP units/mg, powder, BioReagent, suitable for cell culture

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:
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biological source

Porcine intestinal mucosa

Quality Level

type

Grade I-A

product line

BioReagent

form

powder

specific activity

≥180 USP units/mg

technique(s)

analytical sample preparation: suitable, cell culture | mammalian: suitable

color

beige

solubility

H2O: 50 mg/mL

application(s)

advanced drug delivery
cell analysis
diagnostic assay manufacturing
life science and biopharma
sample preparation

SMILES string

[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O

InChI

1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-

InChI key

JRTRSJGZMRQDHI-UHFFFAOYSA-N

General description

Heparin is mainly responsible for the delay in the coagulation of blood. It enhances the antithrombin-mediated inactivation of proteases in the coagulation pathway.
Heparin sodium, a sulfated polysaccharide from the glycosaminoglycan family, plays a vital role in cell culture, cancer biology, and drug discovery research. Its impact on protein and cell interactions makes it valuable for studying molecular and cellular processes, tumor modeling, exploring binding interactions, and as a cell culture supplement to support cell viability.

Application

  • Heparin sodium salt from porcine intestinal mucosa has been used in sLRP (soluble circulating low density lipoprotein receptor-related protein-1) purification from human plasma.
  • It has been used as a supplement in M199 medium for culturing of human umbilical vein endothelial cells.
  • It has been used as an anticoagulant agent during isolation of blood.

Features and Benefits

  • High-purity compound suitable for a wide variety of research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.


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저장 등급

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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문서 라이브러리 방문



Ko-Hsun Liao et al.
PloS one, 12(6), e0179758-e0179758 (2017-06-24)
Tissue angiogenesis is intimately regulated during embryogenesis and postnatal development. Defected angiogenesis contributes to aberrant development and is the main complication associated with ischemia-related diseases. We previously identified the increased expression of RUNX1T1 in umbilical cord blood-derived endothelial colony-forming cells
Factor Xa and thrombin, but not factor VIIa, elicit specific cellular responses in dermal fibroblasts.
Bachli EB et al.
Journal of Thrombosis and Haemostasis, 1, 1935-1935 (2003)
Cristina Di Primio et al.
Frontiers in molecular neuroscience, 10, 210-210 (2017-07-18)
The microtubule (MT)-associated protein Tau is a natively unfolded protein, involved in a number of neurodegenerative disorders, collectively called tauopathies, aggregating in neurofibrillary tangles (NFT). It is an open question how the conversion from a MT bound molecule to an



국제 무역 품목 번호

SKUGTIN
H3149-10KU04061833792681
H3149-100KU04061833792643
H3149-1MU04061833792698
H3149-250KU04061833792728
H3149-25KU04061833792759
H3149-500KU04061833792766
H3149-50KU04061833792773