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78445

Tetrahydrofuran

analytical standard

동의어(들):

Butylene oxide, Oxolane, Tetramethylene oxide

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C4H8O
CAS 번호:
109-99-9
Molecular Weight:
72.11
UNSPSC Code:
12191501
NACRES:
NA.24
PubChem Substance ID:
329768151
EC Number:
203-726-8
Beilstein/REAXYS Number:
102391
MDL number:
MFCD00005356
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도움 문의

grade

analytical standard

Quality Level

100

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

assay

≥99.9% (GC)

autoignition temp.

610 °F

shelf life

limited shelf life, expiry date on the label

contains

~0.025% 2,6-di-tert.-butyl-4-methylphenol as stabilizer

expl. lim.

1.8-11.8 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

solubility

H2O: soluble

density

0.889 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

General description

Tetrahydrofuran (THF) is a saturated cyclic ether. Its potential use as a biofuel for internal combustion engines is investigated.
Tetrahydrofuran is an important basic chemical compound, which belongs to the category of 5-membered heterocycles.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

Tetrahydrofuran may find application as a solvent in the synthesis of (S)-2-(1-pyrrolidinylmethyl)pyrrolidine. It is also an excellent solvent for sodium diisopropylamide, which can find applications as an effective base for the isomerization of alkenes and metalation of 1,4-dienes.
Tetrahydrofuran may be used as an extraction solvent for the determination of pesticide residues in olive oil and phthalates in toys and child care articles by chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Danger

target_organs

Central nervous system, Respiratory system

supp_hazards

EUH019

저장 등급

3 - Flammable liquids

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

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시험 성적서(COA)

Lot/Batch Number

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The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

Learn about analyzing organic volatile impurities (OVIs) in pharmaceuticals using SH-GC, focusing on suitable solvents and ensuring compliance.

Direct Functionalization of Tetrahydrofuran and 1, 4-Dioxane: Nickel-Catalyzed Oxidative C (sp3) H Arylation
Liu D, et al.
Angewandte Chemie (International Edition in English), 52(16), 4453-4456 (2013)
Sodium Diisopropylamide in Tetrahydrofuran: Selectivities, Rates, and Mechanisms of Alkene Isomerizations and Diene Metalations
Algera FR, et al.
Journal of the American Chemical Society, 139(33), 11544-11549 (2017)
Hayashi T, et al. et al.
Asymmetric Synthesis: Graphical Abstracts and Experimental Methods (1998)
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SKUGTIN
78445-5ML-F04061832946580