28514
Methylene Blue hydrate
≥95% (calc. to the dried substance)
동의어(들):
Basic Blue 9 monohydrate ; Methylene Blue (hydrate)
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C16H18ClN3S · xH2O
CAS 번호:
Molecular Weight:
319.85 (anhydrous basis)
UNSPSC Code:
12171500
NACRES:
MA.02
PubChem Substance ID:
EC Number:
200-515-2
Beilstein/REAXYS Number:
3599847
MDL number:
Quality Level
assay
≥95% (calc. to the dried substance)
form
powder
impurities
≤1% insoluble in ethanol
loss
≤22% loss on drying, 105 °C
color
very dark green
solubility
ethanol: insoluble ≤1%
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
O.[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C
InChI
1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
InChI key
WQVSELLRAGBDLX-UHFFFAOYSA-M
General description
Methylene blue is bis(dimethylamino)phenothiazine hydrochloride (tetramethylthionine),
C16H18N3SCl. It is a major basic histological dye in pharmacology and microbiology. This heterocyclic aromatic chemical appears as a dark green solid powder, changing to blue in an aqueous solution. Methylene blue is tested for histological and and bacteriological staining, and as a constituent of Wright’s blood stain.
C16H18N3SCl. It is a major basic histological dye in pharmacology and microbiology. This heterocyclic aromatic chemical appears as a dark green solid powder, changing to blue in an aqueous solution. Methylene blue is tested for histological and and bacteriological staining, and as a constituent of Wright’s blood stain.
Application
Methylene blue is widely used in several routine staining applications including Mallory’s phloxine-methylene blue on paraffin sections of tissue fixed in Zenker’s fluid for nuclear staining and bacterial staining in milk. It is also suitable for manufacturing the polychrome methylene blue used in the preparation of Romanowsky stains.Methylene Blue hydrate has also been used:
- in the preparation of methylene blue (MB) solution
- to stain zymograms -to label the injection site in the tissue slices
- to pre-treat mice via oral gavage to study its effects on noise-induced hearing loss
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Paul J Derry et al.
Nanoscale, 11(22), 10791-10807 (2019-05-28)
Previously, our group reported on the promising efficacy of poly(ethylene glycol)-hydrophilic carbon clusters (PEG-HCCs) to work as broadly active and high capacity antioxidants in brain ischemia and injury models including stroke and traumatic brain injury coupled with hemorrhagic shock. PEG-HCCs
Wei Guo et al.
Acta pharmacologica Sinica, 41(3), 423-431 (2019-06-15)
Indoleamine 2,3-dioxygenase 1 (IDO1) is emerging as a promising therapeutic target for the treatment of malignant tumors characterized by dysregulated tryptophan metabolism. However, the antitumor efficacy of existing small-molecule IDO1 inhibitors is still unsatisfactory, and the underlying mechanism remains largely
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 28514-100G | 04061826259559 |
| 28514-1KG | 04061826714058 |
| 28514-500G | 04061833646274 |