158550
Acridine Orange hemi(zinc chloride) salt
Dye content 85 %
동의어(들):
3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt, 3,6-Bis(dimethylamino)acridinium chloride hemi(zinc chloride salt), Basic Orange 14
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
C17H20ClN3 · HCl · 1/2ZnCl2
CAS 번호:
Molecular Weight:
369.96
UNSPSC Code:
12171500
EC Number:
233-353-6
NACRES:
NA.47
PubChem Substance ID:
MDL number:
Colour Index Number:
46005
Beilstein/REAXYS Number:
3734978
Quality Level
form
powder
composition
Dye content, 85%
solubility
H2O: 1 mg/mL, clear, orange to very deep orange
λmax
489 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Cl[H].Cl[H].Cl[Zn]Cl.CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C.CN(C)c4ccc5cc6ccc(cc6nc5c4)N(C)C
InChI
1S/2C17H19N3.4ClH.Zn/c2*1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;;;;;/h2*5-11H,1-4H3;4*1H;/q;;;;;;+2/p-2
InChI key
RAHGLSRJKRXOSY-UHFFFAOYSA-L
Application
Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.
Acridine Orange hemi (zinc chloride) salt has been used to stain primary human umbilical vein endothelial cells (HUVEC) and is used in micronucleus tests (MNTs).
Biochem/physiol Actions
Acridine orange (AO) is a fluorescent dye with two different staining characteristics. In fixed tissues, it acts as a metachromatic dye and differentially stains DNA (green) and RNA (orange). But, in living cells it acts as a pH indicator and produce brilliant orange-red in acidic condition. AO has been used to identify apoptotic cells in drosophila embryos. Acridine Orange staining method has been used to deliver more consistent data in the micronucleus test.
signalword
Warning
hcodes
Hazard Classifications
Muta. 2
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
관련 콘텐츠
Nancy-520 for DNA Detection and Quantitation
The use of thionin and acridine orange in staining semithin sections of plant material embedded in epoxy resin.
R N Paul
Stain technology, 55(3), 195-196 (1980-05-01)
Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system.
Traganos F
The Journal of Histochemistry and Cytochemistry, 25(1), 46-56 (1977)
Differential staining of apoptotic nuclei in living cells: application to macronuclear elimination in Tetrahymena.
Mpoke SS and Wolfe J.
The Journal of Histochemistry and Cytochemistry, 45(5), 675-683 (1997)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 158550-25G | 04061838744043 |
| 158550-100G | 04061832338675 |
| 158550-10G | 04061838744036 |