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Merck

15527

Glycine

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

동의어(들):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
NH2CH2COOH
CAS 번호:
Molecular Weight:
75.07
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-272-2
MDL number:
Beilstein/REAXYS Number:
635782
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Quality Level

assay

99-101% (based on anhydrous substance)

form

crystalline powder

quality

meets analytical specification of Ph. Eur., BP, USP

technique(s)

IR spectroscopy: suitable

impurities

hydrolyzable substances, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% ninhydrin-positive substances

ign. residue

≤0.1% (as SO4)

loss

≤0.2% loss on drying, 105 °C, 2 h

color

white

pH

5.9-6.4 (20 °C, 5%)

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

H2O: soluble 25 gm in 100 ml at 25 degrees c, H2O: soluble 39.1 gm in 100 ml at 50 degrees c, alcohol: soluble 0.06 gm in 100 gm (Absolute), pyridine: soluble 164 parts, alcohol: very slightly soluble, diethyl ether: very slightly soluble

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

suitability

complies for appearance of solution, complies for reaction against H2SO4, in accordance for identity (IR)

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Application

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Biochem/physiol Actions

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.


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저장 등급

11 - Combustible Solids

ppe

Eyeshields, Gloves, type N95 (US)

flash_point_f

No data available

flash_point_c

No data available



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문서 라이브러리 방문



Jessica T Y Yue et al.
Circulation research, 110(10), 1345-1354 (2012-04-05)
Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the dyslipidemia that leads to cardiovascular morbidity. The central nervous system (CNS), particularly the hypothalamus, regulates hepatic lipid metabolism. Although the underlying neurocircuitry
Tomomi Mito et al.
Reproduction, fertility, and development, 24(3), 443-450 (2012-03-10)
In the present study, the effects of glucose and/or glycine on the in vitro development of Day 5 (Day 0=IVF) porcine blastocysts were determined. The addition of 2.5-10 mM glucose to the chemically defined culture medium porcine zygote medium (PZM)-5
A A Selin et al.
Bulletin of experimental biology and medicine, 153(1), 44-47 (2012-07-19)
Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary



국제 무역 품목 번호

SKUGTIN
15527-1KG-R04061826750650
15527-2.5KG-R04061833605455
15527-6X1KG-R04061833605462
15527-25KG-R04061833440025
15527-500G-R04061833440032