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Merck

MAB3307

Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5

clone 41-1E5, Chemicon®, from mouse

동의어(들):

Fibroblast Collagenase, Interstitial Collagenase

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
41-1E5, monoclonal
Application:
ELISA, IHC, WB
Citations:
24
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

41-1E5, monoclonal

species reactivity

rabbit, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

isotype

IgG2aκ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... MMP1(4312)

General description

52 kDa

Immunogen

Epitope: a.a. 332-350 hMMP1
Syntheic peptide aa332-350 of hMMP-1

Application

Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5 detects level of MMP-1 & has been published & validated for use in ELISA, IH(P) & WB.
Immunoblotting:

Immunohistochemistry on PLP fixed, paraffin-embedded tissues 5-20μg/ml. PLP fixation required for best results. Antibody also reacts with frozen tissues. Reactivity on tradional formalin fixed tissue is poor. Microwave antigen retrieval is recommended

ElA

Biochem/physiol Actions

Specifically reacts with precursor and active forms of human MMP-1.

Physical form

Format: Purified
Liquid in 0.1 M Na-Phosphate buffer, pH 7.0 containing 2% protease free bovine Serum albumin.

Analysis Note

Control
Cervical carcinoma

SKBr-3 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-1122

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



시험 성적서(COA)

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문서 라이브러리 방문



Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts.
Andreea M Bujor,Sashidar Nakerakanti,Erin Morris,Faye N Hant,Maria Trojanowska
Experimental Dermatology null
Immunohistochemical demonstration of collagenase and tissue inhibitor of metalloproteinases (TIMP) in synovial lining cells of rheumatoid synovium
Okada, Y. et al.
Virchows Archiv. B, Cell Pathology Including Molecular Pathology, 59, 305-312 (1990)
Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway.
Deroanne, CF; Hamelryckx, D; Ho, TT; Lambert, CA; Catroux, P; Lapiere, CM; Nusgens, BV
Journal of Cell Science null



국제 무역 품목 번호

SKUGTIN
MAB330708436037124525