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9310-OP

TRIS Hydrochloride

Name: TRIS Hydrochloride
Brand: MM

OmniPur^® Grade, >=99.0%

동의어(들):

Trizma^® hydrochloride, Trizma, Tris(hydroxymethyl)aminomethane, TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:

NH₂C(CH₂OH)₃ · HCl

CAS 번호:

1185-53-1

Molecular Weight:

157.60

NACRES:

NA.25

UNSPSC Code:

12161700

Beilstein/REAXYS Number:

3675235

MDL number:

MFCD00012590

기술 서비스

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도움 문의

속성

Quality Level

100

form

crystalline powder, needles

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

white

useful pH range

7.0-9.0

pKa (25 °C)

8.1

shipped in

ambient

SMILES string

Cl.NC(CO)(CO)CO

InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

설명

General description

Molecular Biology Grade.
260 (10%, water): ≤0.05 AU
A₂₈₀ (10%, water): ≤0.05 AU
Assay: ≥99%
DNAse: none detected
Identity IR spectrum: conforms
Lead (Pb): ≤.0002%
Phosphatase: none detected
Protease: none detected
RNAse: none detected
Water (H₂O): ≤0.5%

Intended for laboratory and manufacturing use only. Not for drug, food, or household use.

Application

Use of tetraethylammonium (TEA) and Tris loading for blocking TRPM7 channels in intact cells.: This study highlights the application of TRIS Hydrochloride in blocking TRPM7 channels, which is significant for cell signaling and ion channel regulation in pharmacological research (Holderby & Kozak, 2024).

Investigating the influence of solvent type and pH on protein adsorption onto silica surface by evanescent-wave cavity ring-down spectroscopy.: This study uses TRIS Hydrochloride to explore protein-silica interactions, providing insights into surface chemistry and biomolecular adsorption processes (Alnaanah & Mendes, 2024).

Other Notes

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c