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481975

(−)-Nicotine hydrogen tartrate salt

≥98% (HPLC), Nicotinic acetylcholine receptor agonist, solid

동의어(들):

(--)-Nicotine, Ditartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di- d-tartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di-d-tartrate

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C10H14N2 · 2C4H6O6
CAS 번호:
65-31-6
Molecular Weight:
462.41
MDL number:
MFCD00069368
UNSPSC Code:
12352210
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze
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제품 이름

(--)-Nicotine, Ditartrate, Potent agonist of the nicotinic acetylcholine receptor.

description

Merck USA index - 14, 6524

Quality Level

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to off-white

solubility

ethanol: 10 mg/mL, water: 10 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

N1(C(CCC1)c2cnccc2)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O

InChI

1S/C10H14N2.2C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t;2*1-,2-/m.11/s1

InChI key

RFEJUZJILGIRHQ-WBPXWQEISA-N

General description

Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Nicotinic acetylcholine receptor
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Rand, M.J. 1989. Prog. Brain Res. 79, 3.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)

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Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2

저장 등급

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

289.8 °F

flash_point_c

143.2 °C

시험 성적서(COA)

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문서 라이브러리 방문

Yan Wang et al.
Oncology reports, 40(4), 2097-2104 (2018-07-18)
Store‑operated calcium entry (SOCE) is critical for regulating the proliferation and metastasis of various cancer types. The present study aimed to investigate the role of SOCE on nicotine‑promoted proliferation of non‑small cell lung cancer (NSCLC) A549 cells. Cell proliferation was

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SKUGTIN
481975-100MG04055977183436