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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C42H83NO3
CAS 번호:
Molecular Weight:
650.11
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
제품 이름
C24:1 Dihydroceramide (d18:0/24:1(15Z)), Avanti Research™ - A Croda Brand 860629P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860629P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860629P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
InChI
1S/C42H83NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,40-41,44-45H,3-16,19-39H2,1-2H3,(H,43,46)/b18-17-/t40-,41+/m0/s1
InChI key
YUULKFVZRXQHPM-ATHUGRIKSA-N
Application
C24:1 Dihydroceramide has been used as a standard in quadrupole time-of-flight (Q-TOF) mass spectrometry for the measurement of sphingolipid metabolites in adipose tissue. It has also been used a standard in diacylglycerol kinase (DGK) assay to quantify dihydroceramides in CLN9-deficient cells.
Biochem/physiol Actions
C24:1 Dihydroceramide is a synthetic dihydroceramide. Dihydroceramides are reduced to ceramides by the enzyme dihydroceramide desaturase. Elevated levels of serum 24:1 DHC has been observed in patients with history of hepatocellular carcinoma (HCC) pre-orthopic liver transplantation (OLT), compared to patients with no prior HCC. Therefore, 24:1 DHC can be used as a HCC biomarker in post-OLT patients.
Packaging
5 mL Amber Glass Screw Cap Vial (860629P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
wgk
WGK 3
C22: 0-and C24: 0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines
Holliday Jr, et al.
PLoS ONE, 8(9) (2013)
The CLN9 protein, a regulator of dihydroceramide synthase
Schulz A, et al.
The Journal of Biological Chemistry, 281(5), 2784-2794 (2006)
C22: 0-and C24: 0-dihydroceramides confer mixed cytotoxicity in T-cell acute lymphoblastic leukemia cell lines
Holliday Jr, et al.
Testing, 8(9) (2013)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 860629P-5MG | 04061835318773 |