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Merck

860576P

Avanti

C16 Lactosyl(β) Ceramide (d18:1/16:0)

Avanti Research™ - A Croda Brand

동의어(들):

D-lactosyl-β-1,1′ N-palmitoyl-D-erythro-sphingosine

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크기 선택

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C46H87NO13
CAS 번호:
4201-62-1
Molecular Weight:
862.18
MDL number:
MFCD08703001
UNSPSC 코드:
12352211
NACRES:
NA.25

주요 문서

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제품 이름

C16 Lactosyl(β) Ceramide (d18:1/16:0), Avanti Research™ - A Croda Brand 860576P, powder

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 5 mg (860576P-5mg)

제조업체/상표

Avanti Research™ - A Croda Brand 860576P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C46H87NO13/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-35(50)34(47-38(51)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)33-57-45-43(56)41(54)44(37(32-49)59-45)60-46-42(55)40(53)39(52)36(31-48)58-46/h27,29,34-37,39-46,48-50,52-56H,3-26,28,30-33H2,1-2H3,(H,47,51)

InChI key

HLIJNIKSBCIDGO-QKLMXXKVSA-N

일반 설명

Lactosylceramide (LacCer) is a glycosphingolipid, which is found majorly in the nervous system and myelin sheath. It comprises a hydrophobic ceramide lipid and a hydrophilic sugar moiety.

애플리케이션

C16 Lactosyl(β) Ceramide (d18:1/16:0) or D-lactosyl-β-1,1′ N-palmitoyl-D-erythro-sphingosine has been used as a lipid standard in mass spectrometry imaging of lipids in human skin disease model hidradenitis suppurativa. It may be used in the preparation of liposomes.

생화학적/생리학적 작용

Lactosylceramide (LacCer) is a structural and signaling lipid. It is crucial for signal transduction and cell adhesion. LacCer facilitates microbial attachment and also acts as an adhesion receptor for pathogens. It regulates cellular stress response and apoptosis. LacCer also modulates in cell proliferation and microbial pathogenesis. It is implicated in innate immune responses, host-tissue pathogen interactions and chronic inflammatory diseases.

포장

5 mL Amber Glass Screw Cap Vial (860576P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

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시험 성적서(COA)

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