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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C42H83NO3
CAS 번호:
Molecular Weight:
650.11
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860524P-10mg), pkg of 1 × 5 mg (860524P-5mg), pkg of 1 × 50 mg (860524P-50mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C42H83NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h35,37,40-41,44-45H,3-34,36,38-39H2,1-2H3,(H,43,46)/b37-35+/t40-,41+/m0/s1
InChI key
ZJVVOYPTFQEGPH-AUTSUKAISA-N
General description
C24 Ceramide has long acyl chain length of 24 carbon units.
Application
C24 Ceramide (d18:1/24:0) has been used:
- in the generation of small unilamellar vesicles
- as an internal standard in liquid chromatography-mass spectrometry for ceramide quantification from rat samples
- to test its effect on mitochondrial stress response in worms
Biochem/physiol Actions
C24 ceramide induces mitochondrial stress response. Its levels are depleted in coronary artery disease (CAD). However, elevated ceramide levels is observed in Alzheimer′s disease. C24 is synthesized during stress. It mediates spontaneous neutrophil death.
Packaging
5 mL Amber Glass Screw Cap Vial (860524P-10mg)
5 mL Amber Glass Screw Cap Vial (860524P-50mg)
5 mL Amber Glass Screw Cap Vial (860524P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
저장 등급
11 - Combustible Solids
Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains
Pullmannova P, et al.
Biophysical Chemistry, 224, 20-31 (2017)
Ceramides and sphingomyelinases in senile plaques
Panchal M, et al.
Neurobiology of Disease, 65, 193-201 (2014)
Grégory Seumois et al.
Journal of leukocyte biology, 81(6), 1477-1486 (2007-03-03)
Neutrophils rapidly undergo spontaneous apoptosis following their release from the bone marrow. Although central to leukocyte homeostasis, the mechanisms that regulate neutrophil apoptosis remain poorly understood. We show here that apoptosis of cultured neutrophils is preceded by a substantial increase
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 860524P-10MG | 04061835317721 |
| 860524P-50MG | 04061835317738 |
| 860524P-5MG | 04061835317745 |