860524P
Avanti
C24 Ceramide (d18:1/24:0)
Avanti Research™ - A Croda Brand
동의어(들):
N-lignoceroyl-D-erythro-sphingosine
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C42H83NO3
CAS 번호:
Molecular Weight:
650.11
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 10 mg (860524P-10mg)
pkg of 1 × 5 mg (860524P-5mg)
pkg of 1 × 50 mg (860524P-50mg)
제조업체/상표
Avanti Research™ - A Croda Brand
지질 유형
sphingolipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C42H83NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h35,37,40-41,44-45H,3-34,36,38-39H2,1-2H3,(H,43,46)/b37-35+/t40-,41+/m0/s1
InChI key
ZJVVOYPTFQEGPH-AUTSUKAISA-N
일반 설명
C24 Ceramide has long acyl chain length of 24 carbon units.
애플리케이션
C24 Ceramide (d18:1/24:0) has been used:
- in the generation of small unilamellar vesicles
- as an internal standard in liquid chromatography-mass spectrometry for ceramide quantification from rat samples
- to test its effect on mitochondrial stress response in worms
생화학적/생리학적 작용
C24 ceramide induces mitochondrial stress response. Its levels are depleted in coronary artery disease (CAD). However, elevated ceramide levels is observed in Alzheimer′s disease. C24 is synthesized during stress. It mediates spontaneous neutrophil death.
포장
5 mL Amber Glass Screw Cap Vial (860524P-10mg)
5 mL Amber Glass Screw Cap Vial (860524P-50mg)
5 mL Amber Glass Screw Cap Vial (860524P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains
Pullmannova P, et al.
Biophysical Chemistry, 224, 20-31 (2017)
Ceramides and sphingomyelinases in senile plaques
Panchal M, et al.
Neurobiology of Disease, 65, 193-201 (2014)
Grégory Seumois et al.
Journal of leukocyte biology, 81(6), 1477-1486 (2007-03-03)
Neutrophils rapidly undergo spontaneous apoptosis following their release from the bone marrow. Although central to leukocyte homeostasis, the mechanisms that regulate neutrophil apoptosis remain poorly understood. We show here that apoptosis of cultured neutrophils is preceded by a substantial increase
Liposome Preparation for the Analysis of Lipid-Receptor Interaction and Efferocytosis
Voss OH, et al.
Current Protocols in Immunology, 120(1), 14-44 (2018)
Lipid biosynthesis coordinates a mitochondrial-to-cytosolic stress response
Kim HE, et al.
Cell, 166(6), 1539-1552 (2016)
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