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Merck

W381918

L-Arginine

99%, FCC, FG

동의어(들):

(S)-2-Amino-5-guanidinopentanoic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
CAS 번호:
Molecular Weight:
174.20
FEMA Number:
3819
UNSPSC Code:
12164502
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.21
EC Number:
200-811-1
Flavis number:
17.003
MDL number:
Beilstein/REAXYS Number:
1725413
Organoleptic:
faint
Grade:
FG
Biological source:
synthetic
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens
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biological source

synthetic

Quality Level

grade

FG

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 872/2012, FCC, FDA 21 CFR 172.320

assay

99%

form

powder or crystals

optical activity

[α]20/D +27°, c = 8 in 6 M HCl

mp

222 °C (dec.) (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

faint

SMILES string

N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

InChI key

ODKSFYDXXFIFQN-BYPYZUCNSA-N

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

General description

L-Arginine is an amino acid that plays a key role in many physiological processes such as tissue repair and reproduction. It is a key precursor for synthesizing nitric oxide in mammals. Due to these factors, the dietary supplementation with L-arginine may show a range of health benefits.

Application


  • Metabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM.: This study employs L-Arginine to examine metabolic changes during the transition from pre-diabetes to type 2 diabetes mellitus, offering new targets for early intervention (Ji et al., 2024 Jun). Link to the article.

  • Amino acid profile alteration in age-related atrial fibrillation.: Investigates the role of L-Arginine in cardiovascular aging, highlighting its potential in developing therapeutic strategies against atrial fibrillation associated with aging (Huang et al., 2024 Mar). Link to the article.

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.


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저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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문서 라이브러리 방문



Blood pressure and metabolic changes during dietary L-arginine supplementation in humans.
Siani A, et al.
American Journal of Hypertension, 13(5), 547-551 (2000)
L-Arginine Research Progress (2012)
Diane N Singhroy et al.
Retrovirology, 10, 73-73 (2013-07-23)
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e.



국제 무역 품목 번호

SKUGTIN
W381918-10KG04061838258106
W381918-1KG04061838258113
W381918-5KG04061838258120
W381918-SAMPLE04061837537509