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902551

BocNH-PEG4-acid

Name: BocNH-PEG4-acid
Brand: ALDRICH

동의어(들):

2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid, Boc-NH-PEG4-CH₂COOH

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):

C₁₅H₂₉NO₈

CAS 번호:

876345-13-0

Molecular Weight:

351.39

MDL number:

MFCD30528568

UNSPSC Code:

12352106

NACRES:

NA.22

Form:

liquid

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도움 문의

속성

form

liquid

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

refractive index

n/D 1.4641

density

1.1395 g/mL

functional group

Boc, amine, carboxylic acid

storage temp.

−20°C

SMILES string

OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O

InChI

1S/C15H29NO8/c1-15(2,3)24-14(19)16-4-5-20-6-7-21-8-9-22-10-11-23-12-13(17)18/h4-12H2,1-3H3,(H,16,19)(H,17,18)

InChI key

SHMYENBXRNPSOG-UHFFFAOYSA-N

설명

Application

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophilic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Other Notes

A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic Applications

A Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

저장 등급

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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국제 무역 품목 번호

SKU	GTIN
902551-1G	04061838693464
902551-250MG	04061838693471