902535
Amino-PEG4-t-butyl ester
동의어(들):
tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate, H2N-PEG4-CH2CH2COOtBu, H2N-dPEG(4)-CO-OtBu
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C15H31NO6
CAS 번호:
Molecular Weight:
321.41
UNSPSC Code:
51171641
NACRES:
NA.22
MDL number:
Form:
liquid
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n/D 1.4508
density
1.04479 g/mL
functional group
amine, ester
storage temp.
−20°C
SMILES string
NCCOCCOCCOCCOCCC(OC(C)(C)C)=O
InChI
1S/C15H31NO6/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h4-13,16H2,1-3H3
InChI key
PKESARRNSGIDRD-UHFFFAOYSA-N
Application
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophilic PEG linker facilitates solubility in biological applications. Amino-PEG4-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Other Notes
Real-time monitoring of vesicle pH in an endocytic pathway using an EGF-conjugated two-photon probe
Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases
A bisphosphonate tweezers and clickable PEGylated PAMAM dendrons for the preparation of functional iron oxide nanoparticles displaying renal and hepatobiliary elimination
Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases
A bisphosphonate tweezers and clickable PEGylated PAMAM dendrons for the preparation of functional iron oxide nanoparticles displaying renal and hepatobiliary elimination
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 902535-1G | 04061838693372 |
| 902535-250MG | 04061838693396 |