900913
Tetrazine-PEG5-NHS ester
≥95%
동의어(들):
Tz-PEG5-NHS
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C27H36N6O10
CAS 번호:
Molecular Weight:
604.61
UNSPSC Code:
12352108
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
powder or crystals
Quality Level
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry, reagent type: linker
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O
InChI
1S/C27H36N6O10/c34-23(28-19-21-1-3-22(4-2-21)27-31-29-20-30-32-27)7-9-38-11-13-40-15-17-42-18-16-41-14-12-39-10-8-26(37)43-33-24(35)5-6-25(33)36/h1-4,20H,5-19H2,(H,28,34)
InChI key
DUPHIQYIPUTDJS-UHFFFAOYSA-N
General description
Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.
Application
Tetrazine-PEG5-NHS ester (Tz-PEG5-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction.
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
문서
Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.
생화학 또는 생체접합 연구에 적합한 가교제를 선택하는 것은 어려운 일입니다. 당사의 선택 가이드는 귀사의 응용분야에 가장 잘 맞는 제품을 찾는 데 도움을 드릴 수 있습니다.
Shape-Encoded Chitosan?Polyacrylamide Hybrid Hydrogel Microparticles with Controlled Macroporous Structures via Replica Molding for Programmable Biomacromolecular Conjugation.
Kang E, et al.
Langmuir, 32(21), 5394-5402 (2016)
Porosity-Tuned Chitosan?Polyacrylamide Hydrogel Microspheres for Improved Protein Conjugation.
Jung S, et al.
Biomacromolecules, 17(7), 2427-2436 (2016)
Amit Kumar et al.
Bioconjugate chemistry, 26(4), 782-789 (2015-03-12)
We report a click-chemistry based modular strategy for antibody labeling with (64)Cu (t1/2 = 12.7 h; β(+) 0.656 MeV, 17.4%; β(-) 0.573 MeV, 39%; EC 43%) under ambient condition utilizing a cross-bridged tetraazamacrocyclic (CB-TE2A) analogue, which otherwise requires harsh conditions
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 900913-50MG | 04061833251409 |