์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

900892

L-Azidohomoalanine hydrochloride

๋™์˜์–ด(๋“ค):

AHA

์กฐ์ง ๋ฐ ๊ณ„์•ฝ ๊ฐ€๊ฒฉ์„ ๋ณด๋ ค๋ฉด ๋กœ๊ทธ์ธ๋ฅผ ํด๋ฆญํ•ฉ๋‹ˆ๋‹ค.

ํฌ๊ธฐ ์„ ํƒ

๋ณด๊ธฐ ๋ณ€๊ฒฝ

์ œํ’ˆ์ •๋ณด (DICE ๋ฐฐ์†ก ์‹œ ๋น„์šฉ ๋ณ„๋„)

์‹คํ—˜์‹(Hill ํ‘œ๊ธฐ๋ฒ•):
C4H8N4O2 ยท HCl
CAS ๋ฒˆํ˜ธ:
Molecular Weight:
180.59
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.21
๊ธฐ์ˆ  ์„œ๋น„์Šค
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๋„์›€ ๋ฌธ์˜


form

powder or crystals

Quality Level

reaction suitability

reaction type: click chemistry

mp

139 ยฐC

storage temp.

−20ยฐC

SMILES string

[Cl-].[N+H3][C@@H](CCN=[N+]=[N-])C(=O)O

InChI

1S/C4H8N4O2.ClH/c5-3(4(9)10)1-2-7-8-6;/h3H,1-2,5H2,(H,9,10);1H/t3-;/m0./s1

InChI key

MHHYJRIDKLZZEO-DFWYDOINSA-N

Application

L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or โ€œclick โ€ reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.


pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Self-react. C

์ €์žฅ ๋“ฑ๊ธ‰

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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์‹œํ—˜ ์„ฑ์ ์„œ(COA)

Lot/Batch Number

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๋ชจ๋“  ๊ธฐ์‚ฌ ๋ณด๊ธฐ

Expanding the diversity of chemical protein modification allows post-translational mimicry.
van Kasteren S I, et al.
Nature, 446(7139), 1105-1105 (2007)
Teresa Rayon et al.
Science (New York, N.Y.), 369(6510) (2020-09-19)
Although many molecular mechanisms controlling developmental processes are evolutionarily conserved, the speed at which the embryo develops can vary substantially between species. For example, the same genetic program, comprising sequential changes in transcriptional states, governs the differentiation of motor neurons



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900892-100MG04061833251362