900863
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
≥95%
동의어(들):
3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol, Hydroxyl diazirine alkyne, Probe building block
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C7H10N2O
CAS 번호:
Molecular Weight:
138.17
UNSPSC Code:
12352200
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
liquid
Quality Level
assay
≥95%
form
liquid
density
1.08 g/mL
storage temp.
−20°C
SMILES string
OCCC1(N=N1)CCC#C
InChI
1S/C7H10N2O/c1-2-3-4-7(5-6-10)8-9-7/h1,10H,3-6H2
InChI key
NMIZSJAOOMXKDJ-UHFFFAOYSA-N
Application
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes
Technology Spotlight: Trifunctional Probe Building Blocks
Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases
In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors
Reversible inhibitors arrest ClpP in a defined conformational state that can be revoked by ClpX association
Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling
저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
문서
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 900863-50MG | 04061833251294 |