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779776

Methyl-β-cyclodextrin

Name: Methyl-β-cyclodextrin
Brand: ALDRICH

Wacker Chemie AG, ≥95.0% cyclodextrin basis (calculated)

동의어(들):

Cavasol^® W7 M, Methyl-beta-cyclodextrin

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제품정보 (DICE 배송 시 비용 별도)

CAS 번호:

128446-36-6

MDL number:

MFCD00066764

UNSPSC Code:

12352201

NACRES:

NA.22

Assay:

≥95.0% cyclodextrin basis (calculated)

Form:

powder

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도움 문의

속성

Quality Level

100

assay

≥95.0% cyclodextrin basis (calculated)

form

powder

manufacturer/tradename

Wacker Chemie AG

extent of labeling

1.6-1.9 molar substitution

impurities

≤0.2% unsubstituted cyclodextrin, ≤0.2% volatile organics, ≤2% chloride

loss

≤7.0% loss on drying

mp

180-182 °C (lit.)

SMILES string

O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

InChI key

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

설명

Application

Methyl-β-cyclodextrin (M-β-CD) can be used as a reactant to prepare ternary inclusion complex of diclofenac (DCF) in the presence of monoethanolamine (MEA). This complex improves the percutaneous absorption of DCF in human skin. It can also be used to form an inclusion complex with olanzapine (OLP) to increase its solubility for efficient drug delivery.

Other Notes

For R&D Use

Legal Information

Cavasol is a registered trademark of Wacker Chemie AG

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저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

368.6 °F

flash_point_c

187 °C

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시험 성적서(COA)

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Synthesis and characterization of binary and ternary complexes of diclofenac with a methyl-beta-CD and monoethanolamine and in vitro transdermal evaluation.

María Julia Mora et al.

European journal of medicinal chemistry, 45(9), 4079-4088 (2010-06-23)

Here, we describe the chemical characterization of the inclusion complex between diclofenac (DCF) and methyl-beta-cyclodextrin (M-beta-CD) in the presence or absence of monoethanolamine (MEA). Several techniques were used to analyze the complex both in solution and in the solid state.

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국제 무역 품목 번호

SKU	GTIN
779776-100G	04061832941127
779776-10KG	04061833381380
779776-500G	04061833552377