420069
4,5-Dimethoxy-2-nitrobenzyl chloroformate
97%, for peptide synthesis
동의어(들):
6-Nitroveratryl chloroformate, 6-Nitroveratryloxycarbonyl chloride, NVOC chloride, NVOC-Cl
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
ClCO2CH2C6H2(OCH3)2NO2
CAS 번호:
Molecular Weight:
275.64
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352101
MDL number:
Beilstein/REAXYS Number:
2389168
제품 이름
4,5-Dimethoxy-2-nitrobenzyl chloroformate, 97%
Quality Level
assay
97%
form
powder
mp
125 °C (dec.) (lit.)
application(s)
peptide synthesis
functional group
chloro, nitro
storage temp.
2-8°C
SMILES string
COc1cc(COC(Cl)=O)c(cc1OC)[N+]([O-])=O
InChI
1S/C10H10ClNO6/c1-16-8-3-6(5-18-10(11)13)7(12(14)15)4-9(8)17-2/h3-4H,5H2,1-2H3
InChI key
RWWPKIOWBQFXEE-UHFFFAOYSA-N
Application
4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups. General applications are:
- Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.
- Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.
- Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
저장 등급
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Photolabile protecting groups for nucleosides: Synthesis and photodeprotection rates.
Hasan A, et al.
Tetrahedron, 53(12), 4247-4264 (1997)
Photoremovable protecting groups in organic synthesis.
Pillai V R
Synthesis, 1980(01), 1-26 (1980)
A general and efficient route for chemical aminoacylation of transfer RNAs.
Robertson S A, et al.
Journal of the American Chemical Society, 113(7), 2722-2729 (1991)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| 420069-1G | 04061826732656 |