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Merck

308560

4-Amino-6-chloro-1,3-benzenedisulfonamide

98%

동의어(들):

3-Chloroaniline-4,6-disulfonamide, 4-Amino-6-chlorobenzene-1,3-disulfonamide

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
H2NC6H2(Cl)(SO2NH2)2
CAS 번호:
Molecular Weight:
285.73
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-463-1
Beilstein/REAXYS Number:
1083877
MDL number:
Assay:
98%
Form:
powder
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도움 문의


assay

98%

form

powder

mp

257-261 °C (lit.)

functional group

chloro

SMILES string

Nc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI

1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)

InChI key

IHJCXVZDYSXXFT-UHFFFAOYSA-N

Gene Information

General description

4-Amino-6-chloro-1,3-benzenedisulfonamide is a potent inhibitor of gastric pathogen, Helicobacter pylori (hpCA).

Application

4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes.


저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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문서 라이브러리 방문



Mario Thevis et al.
Analytical chemistry, 74(15), 3802-3808 (2002-08-15)
The mass spectrometric behavior of 21 thiazide-based compounds after electrospray ionization in the negative ion mode and collision-induced dissociation was investigated on a triple-stage quadrupole mass spectrometer. The mass spectra show individual and common fragmentation patterns, the generations of which
B R Thomas et al.
Journal of chromatography. B, Biomedical applications, 657(2), 383-394 (1994-07-15)
A stability-indicating, quality control analysis method was developed and validated for the diuretic drug substances hydrochlorothiazide (HCTZ) and chlorothiazide (CTZ). Micellar electrokinetic capillary chromatography employing the anionic detergent sodium dodecyl sulfate at 30 mM in 20 mM sodium borate buffer
Biopharmaceutical studies of thiazide diuretics. III. In vivo formation of 2-amino-4-chloro-m-benzenedisulfonamide as a metabolite of hydrochlorothiazide in a patient.
T Okuda et al.
Chemical & pharmaceutical bulletin, 35(8), 3516-3518 (1987-08-01)



국제 무역 품목 번호

SKUGTIN
308560-100G04061826674826
308560-5G04061826674840