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Merck

142859

Difluoroacetic acid

98%

동의어(들):

1,1-Difluoroacetic acid, 2,2-Difluoroacetic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
F2CHCO2H
CAS 번호:
Molecular Weight:
96.03
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-839-0
Beilstein/REAXYS Number:
1098588
MDL number:
Assay:
98%
Form:
liquid
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Quality Level

assay

98%

form

liquid

refractive index

n20/D 1.344 (lit.)

bp

132-134 °C (lit.)

mp

−1 °C (lit.)

density

1.526 g/mL at 25 °C (lit.)

functional group

carboxylic acid, fluoro

SMILES string

OC(=O)C(F)F

InChI

1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)

InChI key

PBWZKZYHONABLN-UHFFFAOYSA-N

General description

Difluoroaceticacid is a monocarboxylic acid and an organofluorine compound. Difluoroaceticacid is easy-to-handle reagent, useful for obtaining difluoromethyl substituents. Difluoroacetic acid can be used asdifluoromethylating reagent for the direct C−H difluoromethylation ofheteroaromatic compounds.

Application

Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.


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CorrosionExclamation mark

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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

저장 등급

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

172.4 °F - closed cup

flash_point_c

78 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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문서 라이브러리 방문



N Illy et al.
Comptes rendus des seances de la Societe de biologie et de ses filiales, 175(2), 242-246 (1981-01-01)
Our experiments were carried out in normal and streptozotocin-diabetic rats. The effects of sodium difluoroacetate (DFA) at the dose of 40 mg/kg daily were studied on the blood and retinal lactate levels; these effects were compared to those of an
Brian M Wagner et al.
Journal of chromatography. A, 1489, 75-85 (2017-02-19)
To facilitate mass transport and column efficiency, solutes must have free access to particle pores to facilitate interactions with the stationary phase. To ensure this feature, particles should be used for HPLC separations which have pores sufficiently large to accommodate
Tetrahedron Letters, 48, 3251-3251 (2007)



국제 무역 품목 번호

SKUGTIN
142859-25G04061838118004
142859-5G04061838734501