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850365C

Avanti

18:0 PC (DSPC)

Avanti Research™ - A Croda Brand

Synonyme(s) :

1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; DSPC; PC(18:0/18:0)

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A propos de cet article

Formule empirique (notation de Hill) :
C44H88NO8P
Numéro CAS:
816-94-4
Poids moléculaire :
790.15
MDL number:
MFCD00036905
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1,2-distearoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850365C-25mg), pkg of 1 × 20 mL (850365C-500mg), pkg of 2 × 20 mL (850365C-1g), pkg of 2 × 4 mL (850365C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (850365C-25mg), 25 mg/mL (850365C-1g), 25 mg/mL (850365C-200mg), 25 mg/mL (850365C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:0 PC (DSPC) has been used in the preparation of microbubbles (MBs). It is suitable for use in the synthesis of methylene blue (MB)-liposome synthesis and in the preparation of unilamellar vesicles

Biochem/physiol Actions

18:0 PC (DSPC) liposomes/1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, along with Rhamnolipids (RLs) can serve as the best combination for drug delivery application. It can help to maintain the stability of curcumin.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-1g)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-500mg)
5 mL Clear Glass Sealed Ampule (850365C-200mg)
5 mL Clear Glass Sealed Ampule (850365C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Interaction of curcumin with 1, 2-dioctadecanoyl-sn-glycero-3-phosphocholine liposomes: Intercalation of rhamnolipids enhances membrane fluidity, permeability and stability of drug molecule
Moussa Z, et al.
Colloids and Surfaces. B, Biointerfaces, 149, 30-37 (2017)
Methylene-Blue-Encapsulated Liposomes as Photodynamic Therapy Nano Agents for Breast Cancer Cells
Wu PT, et al.
Nanomaterials, 9(1), 14-14 (2019)
Ana Reis et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183133-183133 (2019-12-01)
Food polyphenols in fruits juices, tea, coffee, wine and beer confer sensory properties such as colour, astringency and bitterness. The development of functional healthy drinks without the unpleasant sensory feeling is boosting research for a clearer understanding on the interactions
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Numéro d'article de commerce international

RéférenceGTIN
850365C-1G04061837792212
850365C-25MG04061837792236
850365C-200MG04061837792229
850365C-500MG04061837792243