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840457C

Avanti

16:0-18:1 PG

Avanti Research™ - A Croda Brand

Synonyme(s) :

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); POPG; PG(16:0/18:1(9Z)); 110650

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A propos de cet article

Formule empirique (notation de Hill) :
C40H76O10PNa
Numéro CAS:
268550-95-4
Poids moléculaire :
770.99
MDL number:
MFCD00674290
UNSPSC Code:
12352211
NACRES:
NA.25
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description

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840457C-25mg), pkg of 2 × 20 mL (840457C-1g), pkg of 2 × 4 mL (840457C-200mg), pkg of 5 × 4 mL (840457C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (840457C-25mg), 25 mg/mL (840457C-1g), 25 mg/mL (840457C-200mg), 25 mg/mL (840457C-500mg)

lipid type

phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC(O)CO

InChI

1S/C40H77O10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,37-38,41-42H,3-16,19-36H2,1-2H3,(H,45,46);/q;+1/p-1/b18-17-;/t37?,38-;/m1./s1

InChI key

FJXDNGDRHUDFST-XQYKCTAGSA-M

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 16:0-18:1 PG/1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (POPG) is an anionic lipid, which possesses one negative charge per lipid.

Application

16:0-18:1 PG has been used in liposome preparation. It is suitable for use as a component in monoolein to treat purified β2-adrenergic receptor (β2AR)-T4 lysozyme (T4L)- Gαs α5 helix (GsCT)-CC chimera protein and in lipid vesicle preparation.

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840457C-1g)
5 mL Clear Glass Sealed Ampule (840457C-200mg)
5 mL Clear Glass Sealed Ampule (840457C-25mg)
5 mL Clear Glass Sealed Ampule (840457C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Lot/Batch Number

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Consulter la Bibliothèque de documents

Membrane Structure and Dynamics
Cell Biology, 227-239 (2017)
Lipids
Medical Biochemistry, 99-119 (2017)
Ionization Properties of Phospholipids Determined by Zeta Potential Measurements
Sathappa M and Alder NN
Bio-protocol, 6(22) (2016)
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Numéro d'article de commerce international

RéférenceGTIN
840457C-200MG04061837791550
840457C-500MG04061837791574
840457C-1G04061837791543
840457C-25MG04061837791567