콘텐츠로 건너뛰기
Merck

HSTCMAG-28SK

MILLIPLEX® Human High Sensitivity T Cell Panel

Configurable 96-well Human High Sensitivity T Cell 21-Plex Panel

동의어(들):

Human high-sensitivity cytokine multiplex kit, Luminex® human high-sensitivity cytokine immunoassay, Millipore human high-sensitivity cytokine panel

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000


제품 이름

MILLIPLEX® Human High Sensitivity T Cell Panel,

Quality Level

description

Configurable 96-well Human High Sensitivity T Cell 21-Plex Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

serum
plasma
cell culture supernatant(s)

assay range

accuracy: 98-107%, sensitivity: 0.11-8.17 pg/mL
(Overnight Incubation minDC), standard curve range: 0.18-750 pg/mL
(IL-6), standard curve range: 0.24-1,000 pg/mL
(IL-13), standard curve range: 0.24-1,000 pg/mL
(IL-21), standard curve range: 0.31-1,250 pg/mL
(IL-8), standard curve range: 0.31-1,250 pg/mL
(MIP-1α), standard curve range: 0.37-1,500 pg/mL
(IL-7), standard curve range: 0.45-1,750 pg/mL
(TNFα), standard curve range: 0.49-2,000 pg/mL
(IL-1β), standard curve range: 0.49-2,000 pg/mL
(IL-12 (p70)), standard curve range: 0.49-2,000 pg/mL
(IL-2), standard curve range: 0.49-2,000 pg/mL
(IL-5), standard curve range: 0.61-2,500 pg/mL
(IFNγ), standard curve range: 0.61-2,500 pg/mL
(MIP-3α), standard curve range: 0.73-3,000 pg/mL
(IL-17A), standard curve range: 0.92-3,750 pg/mL
(MIP-1β), standard curve range: 1.22-5,000 pg/mL
(GM-CSF), standard curve range: 1.46-6,000 pg/mL
(IL-10), standard curve range: 1.46-6,000 pg/mL
(ITAC), standard curve range: 1.83-7,500 pg/mL
(IL-4), standard curve range: 18.3-75,000 pg/mL
(Fractalkine), standard curve range: 7.93-32,500 pg/mL
(IL-23), inter-assay cv: <15%
intra-assay cv: <10%

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Cytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells and myeloid cells. Consequently, research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process. Low levels of inflammation are involved in many sub-clinical disease states, such as autoimmune disease, cardiovascular disease, diabetes, neurological disorders, and cancer. Measuring picogram levels of cytokines, therefore, is critical for understanding the pathogenesis of these diseases.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 21 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: Fractalkine, GM-CSF, IFNγ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-13, IL-17A, IL-21, IL-23, I-TAC, MIP-1α, MIP-1β, MIP-3α, TNF-α

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • High-Sensitivity Detection: Enables the detection of low-abundance T cell cytokines, providing critical insights into subtle immune responses and enhancing understanding of disease mechanisms.
  • Simultaneous Quantification of Multiple Analytes: Capable of measuring a variety of T cell-related cytokines and chemokines in a single assay run, including IL-1β, IL-2, IL-6, IL-10, TNFα, and others, saving time and resources.
  • Versatile Sample Compatibility: Offers flexibility in sample types, making the assay applicable to a wide range of research settings and experimental designs.
  • Enhanced Understanding of Immune Responses: Contributes to a deeper understanding of the immune system′s complex interactions, particularly in the context of inflammatory diseases and other clinical conditions.
  • Cardiovascular Risk Profiling: Analyze IFN-γ and MIP-1α, associated with atherosclerotic plaque instability to identify biomarkers for cardiovascular event prediction or therapeutic monitoring.
  • Subpanel Flexibility: Select subsets of analytes (e.g., IL-2, IL-4, IL-5) for focused hypotheses, reducing costs and streamline workflows for targeted immune monitoring.

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Luminex is a registered trademark of Luminex Corporation

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


Still not finding the right product?

Explore all of our products under


signalword

Danger

target_organs

Respiratory Tract

저장 등급

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2

wgk

WGK 3



시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문


관련 콘텐츠

Immunology multiplex assays, like MILLIPLEX® assays, allow researchers to investigate more immune biomarkers simultaneously, saving time and resources.

MILLIPLEX® 분석과 같은 면역학 멀티플렉스 분석을 통해 연구자들은 더 많은 면역 바이오마커를 동시에 조사할 수 있어 시간과 자원을 절약합니다. 이는 수많은 분석 물질이 다양한 경로에서 역할을 하는 면역학 연구에 특히 중요합니다.

관련 콘텐츠 모두 보기

Yu-Fei Gao et al.
International journal of ophthalmology, 12(11), 1708-1713 (2019-11-20)
To compare the anti-inflammatory effects of intense pulsed light (IPL) with tobramycin/dexamethasone plus warm compress through clinical signs and cytokines in tears. Eighty-two patients with dry eye disease (DED) associated meibomian gland dysfunction (MGD) were divided into two groups. Group
Bruna M Ascoli et al.
International journal of bipolar disorders, 7(1), 13-13 (2019-06-04)
Innate immune system dysfunction has been recognized as an important element in the pathophysiology of bipolar disorder (BD). We aimed to investigate whether there are differences in the response of macrophages derived from patients in the early stages and late
B Karshikoff et al.
Brain, behavior, and immunity, 57, 38-46 (2016-04-09)
Low-grade systemic inflammation has been implicated in chronic pain, as well as in comorbid diseases like depression and fatigue. We have previously shown that women's pain perception and regulation is more affected by systemic inflammation than that of men. Here