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Merck

PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

동의어:
AGM7, GRB1, p85, p85-ALPHA
:
UniProtKB ID:
Clone ID:
  • Human(5295) Summary: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
  • Mouse(18708) phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
  • Rat(25513) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • Zebrafish(557176) phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
  • chicken(427171) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic cat(100271864) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • dog(487235) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • cow(282307) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • sheep(101121455) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic guinea pig(100730242) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PIK3R1 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-PI3 Kinase Antibody, p85, from rabbit, purified by affinity chromatography,
종별 반응성
bovine, human, mouse, rat, rhesus monkey
응용분야
immunoprecipitation (IP)
western blot
Anti-PI3 Kinase Antibody, p85, N-SH3, clone AB6, clone AB6, Upstate®, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Phospho-PI3KP85α/γ/β-Y467/Y199/Y464 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-PI3 Kinase Antibody, p85 Antibody, N-SH3 Antibody, clone 1D5.1, clone 1D5.1, from mouse,
종별 반응성
human, mouse
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Wortmannin, Ready Made Solution, from Penicillium funiculosum, ≥95% (HPLC),
human
Wortmannin, from Penicillium funiculosum, ≥98% (HPLC and TLC),
human
Diphenyleneiodonium chloride, ≥98%,
mouse, human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PIK3R1,
human
MISSION® esiRNA, targeting mouse Pik3r1,
mouse