1613655
USP
Sodium bicarbonate
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
Sodium hydrogen carbonate
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About This Item
Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
Beilstein/REAXYS Number:
4153970
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
sodium bicarbonate
manufacturer/tradename
USP
pH
8.3 (0.1 molfreshly prepared)
pKa (25 °C)
(1) 6.37, (2) 10.25 (carbonic acid)
density
2.16 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
[Na+].OC([O-])=O
InChI
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
InChI key
UIIMBOGNXHQVGW-UHFFFAOYSA-M
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Sodium bicarbonate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Potassium and Sodium Bicarbonates and Citric Acid Effervescent Tablets for Oral Solution
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Qian Liang et al.
Electrophoresis, 36(5), 731-736 (2014-11-26)
Although the existing theories have predicted enhancement of electrophoretic mobility of microparticles near a solid wall, the relevant experimental studies are rare. This is mainly due to difficulties in experimentally controlling and measuring particle-wall separations under dynamic electrophoretic conditions. This
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