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MilliporeSigma

1601827

USP

Residual Solvent Class 2 - Trichloroethylene

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Trichloroethylene solution, Trichloroethene

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About This Item

CAS Number:
79-01-6
EC Number:
201-167-4
MDL number:
MFCD00000838
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

pharmaceutical primary standard

form

solution

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

single component solution

SMILES string

ClC(=CCl)Cl

InChI

1S/C2HCl3/c3-1-2(4)5/h1H

InChI key

XSTXAVWGXDQKEL-UHFFFAOYSA-N

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General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Residual Solvent Class 2 - Trichloroethylene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

closed cup - does not flash

flash_point_c

closed cup - does not flash

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Certificates of Analysis (COA)

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Yih-Horng Shiao
Environmental and molecular mutagenesis, 50(1), 68-77 (2008-11-26)
Trichloroethylene (TCE), an organic solvent commonly used for metal degreasing and as a chemical additive, is a significant environmental contaminant that poses health concerns in humans. The US Environmental Protection Agency (EPA) is currently revising the 2001 TCE human risk
Jane C Caldwell et al.
Environmental and molecular mutagenesis, 49(2), 142-154 (2007-11-02)
The mode(s) of action (MOA) of a pollutant for adverse health effects may be dependent on the mixture of metabolites resulting from exposure to a single agent and may also be affected by coexposure to pollutants that have similar targets
Cheryl Siegel Scott et al.
International journal of environmental research and public health, 8(11), 4238-4272 (2011-12-14)
We conducted a meta-analysis focusing on studies with high potential for trichloroethylene (TCE) exposure to provide quantitative evaluations of the evidence for associations between TCE exposure and kidney, liver, and non-Hodgkin lymphoma (NHL) cancers. A systematic review documenting essential design
[Advance of research on trichloroethylene-induced medicamentosa like dermatitis].
Li-Hua Xia et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 24(12), 764-766 (2007-01-24)
Amy Lavin Williams et al.
International journal of toxicology, 27(1), 81-95 (2008-02-23)
An evaluation of the scientific literature for trichloroethylene (TCE) identified two reports of ocular defects, specifically microphthalmia/anophthalmia, following prenatal TCE exposure in rats. Herein, these reports are analyzed in detail and interpreted within the context of other developmental TCE exposure
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