1379183
USP
Melamine
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
2,4,6-Triamino-1,3,5-triazine, sym-Triaminotriazine
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About This Item
Empirical Formula (Hill Notation):
C3H6N6
CAS Number:
Molecular Weight:
126.12
Beilstein/REAXYS Number:
124341
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
melamine
manufacturer/tradename
USP
mp
>300 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Nc1nc(N)nc(N)n1
InChI
1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)
InChI key
JDSHMPZPIAZGSV-UHFFFAOYSA-N
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General description
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Melamine USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as metformin Hydrochloride
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Repr. 2 - STOT RE 2
target_organs
Urinary tract
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
572.0 °F - closed cup
flash_point_c
300 °C - closed cup
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S A Tittlemier
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 27(2), 129-145 (2010-01-06)
In recent years, two adulteration incidents concerning the addition of melamine (MEL) and related compounds to dairy products and vegetable proteins have occurred in China. These episodes prompted numerous governmental and private laboratories to develop or implement methods for the
Yu-Chang Tyan et al.
Analytical and bioanalytical chemistry, 395(3), 729-735 (2009-08-12)
In the summer of 2008, serious illnesses and deaths of babies in China were linked to melamine-tainted powdered infant formula. Melamine contains several metabolites, such as ammeline, ammelide, and cyanuric acid, and has been used for the adulteration of foods
Yuejiao Wei et al.
Toxicology and industrial health, 28(7), 579-582 (2011-10-12)
In September 2008, in China, tens of thousands of children were hospitalized, several even died, as a result of infant-formula milk adulterated with a synthetic chemical compound, melamine, and in the next few months, this crisis became the focus of
Michael F Neerman et al.
International journal of pharmaceutics, 281(1-2), 129-132 (2004-08-04)
Cell-based and acute and subchronic in vivo toxicity profiles of a dendrimer based on melamine reveal that this class of molecules warrants additional study as vehicles for drug delivery. In cell culture, a substantial decrease in viability was observed at
Anthony Kai-ching Hau et al.
Journal of the American Society of Nephrology : JASN, 20(2), 245-250 (2009-02-06)
The toxicity of melamine caught the attention of physicians as a result of a recent spate of renal injury after exposure to melamine-tainted milk in China. Melamine is an organic nitrogenous compound used in the production of plastics, dyes, fertilizers
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