1065618
USP
Betahistine hydrochloride
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
Betahistine dihydrochloride, Methyl[2-(2-pyridyl)ethyl]amine dihydrochloride
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About This Item
Empirical Formula (Hill Notation):
C8H12N2 · 2HCl
CAS Number:
Molecular Weight:
209.12
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
betahistine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Cl.CNCCc1ccccn1
InChI
1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H
InChI key
XVDFMHARQUBJRE-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269), HRH3(11255)
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Betahistine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human
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