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About This Item
NACRES:
NB.21
UNSPSC Code:
41115712
material
PE frit (20 μm), polypropylene hardware
quality
MS friendly
composition
bed wt., 60 mg
packaging
pk of 50
technique(s)
solid phase extraction (SPE): suitable
surface area
160-420 m2/g
volume
3 mL
matrix
Hydrophilic modified styrene polymer particle platform
matrix active group
polystyrene phase
particle size
50-70 μm
pore size
80-200 Å pore size
application(s)
food and beverages
separation technique
reversed phase
General description
Retention Mechanism: Reversed-phase
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)
Sample Matrix Compatibility: Aqueous solutions (biological fluids, water)
- Hydrophilic modified styrene polymer
- Developed for the extraction of a highly broad range of compounds from aqueous samples
- Retention predominately based on reversed-phase; however, because the phase is hydrophilic modified, it is amenable to polar compounds as well.
- Examples of more polar compounds that are retained and recovered include (but not limited to): pyridoxine (logPo/w -0.56), riboflavin (logPo/w -2.02), biotin (logPo/w 0.11).
Application
Supel™-Select HLB SPE Tube may be used as an extraction cartridge for the solid phase extraction and determination of antibiotics in water samples using liquid chromatography electrospray ionization tandem mass spectrometry.
Features and Benefits
- Excellent sample prep performance at a lower price
- Amenable to generic methodology - save time, money, and headache during method development
- Greater capacity allows for smaller bed weights = smaller elution volumes = time savings in sample processing
- Resistance to overdrying allows for more robust methdology
- Low UV and MS extractables for lower background and greater sensitivity
- Stringent production and QC guidelines offer greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision
Legal Information
Supel is a trademark of Sigma-Aldrich Co. LLC
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Reversed-phase interaction will retain most molecules with hydrophobic character; it is very useful for extracting analytes that are very diverse in structure within the same sample.
Analysis of selected antibiotics in surface freshwater and seawater using direct injection in liquid chromatography electrospray ionization tandem mass spectrometry
Bayen S, et al.
Journal of Chromatography A, 1338, 38-43 (2014)
Chiedza F Munyeza et al.
Biomedical chromatography : BMC, 30(6), 837-845 (2015-09-18)
Tigecycline (TIG), a derivative of minocycline, is the first in the novel class of glycylcyclines and is currently indicated for the treatment of complicated skin structure and intra-abdominal infections. A selective, accurate and reversed-phase high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)
Pablo Vazquez-Roig et al.
Analytical and bioanalytical chemistry, 397(7), 2851-2864 (2010-05-01)
A simple and robust method using solid-phase extraction (SPE) and liquid chromatography tandem mass spectrometry (LC-MS/MS) for the simultaneous determination of 14 drugs of abuse and their metabolites (cocainics, amphetamine-like compounds, cannabinoids, and opiates) in surface waters has been developed.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 54182-U | 04061835552207 |