10471
Carboxen® Adsorbent
matrix Carboxen® 1003, 40-60 mesh, bottle of 10 g
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About This Item
EC Number:
UNSPSC Code:
23201100
product line
Carboxen®
Quality Level
form
powder
packaging
bottle of 10 g
technique(s)
LPLC: suitable
surface area
~1000 m2/g
matrix
Carboxen® 1003
matrix active group
carbon
particle size
40-60 mesh
pore size
~0.26 cm3/g mesoporosity
~0.28 cm3/g macroporosity
~0.38 cm3/g microporosity
~5-8 Å pore diameter
density
~0.49 g/mL (free fall density)
separation technique
reversed phase
General description
Carboxen® 1003 was used for the adsorption of lipopolysaccharides (LPS) as it can accommodate large LPS and their agglomerates.
Carboxen® Adsorbent is ideally used for solid-phase microextraction (SPME). It is highly efficient in extraction of small polar molecules from aqueous solution.
Carboxens are a highly engineered synthetic carbon adsorbent engineered from polymeric precursors. These particles will not plastically deform like resins or generate fines like activated carbon. These materials are shipped and stored dried. These derivatized resins bring value to a wide range of purification applications for removing both small and large molecule impurities. They find use in both gas and liquid phase purifications. Some examples include removal of homogenous catalysts from active pharmaceutical ingredients (API)s, high-risk impurities in biochemical purifications such as host cell proteins from mAbs, removal of toxic heavy metals, purification of chlorinated molecules, and removal of extractables and leachables. Tapered pores result in increased thermodynamic and kinetic properties for both adsorption and desorption. The Carboxens vary in the relative percentage of pore structures (micro, meso, and macro), surface area, and surface pH.
Features and Benefits
Features and Benefits:
- Spherical
- Hard (ball pan hardness >98%)
- Stable up to 400°C
- High purity
- Easy to pack
- Stable over entire pH range
- Do not create backpressure
- High osmotic shock stability
- Tapered pore sizing (from macro- to meso- to micro-)
Other Notes
For more information, please visit: specialty Carbon Adsorbents
Legal Information
Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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Adsorption of lipopolysaccharide on carbon sieves.
Gun'Ko VM, et al.
Carbon, 44 (7), 1258-1262 (2006)
Applications of Solid Phase Microextraction.
Pawliszyn J.
Science, 64-65 (1999)
Frank Sporkert et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 772(1), 45-51 (2002-05-23)
A new and in part automated headspace solid-phase microextraction method for quantitative determination of the highly toxic rodenticide fluoroacetic acid (FAA) in serum and other biological samples has been developed. FAA and deuterated acetic acid (internal standard) were extracted from
Filippo Maggi et al.
Chemistry & biodiversity, 8(1), 95-114 (2011-01-25)
Headspace solid-phase microextraction (HS-SPME) coupled with GC/FID and GC/MS was applied for the first time in the analysis of the volatile fraction of an Ephedra species. Notably, six Italian populations (Marche, Abruzzo, and Sardinia) of Ephedra nebrodensis subsp. nebrodensis, covering
B D Page et al.
Journal of chromatography. A, 873(1), 79-94 (2000-04-11)
The headspace solid-phase microextraction (HS-SPME) efficiencies from vegetable oil of the recently available Carboxen-poly(dimethylsiloxane) (PDMS) and divinylbenzene-Carboxen-PDMS fibres were found to be much greater than those of the PDMS fibre for a number of volatile contaminants. Using these Carboxen-based fibres
Articles
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