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SRP0428

PDE2A active rat

recombinant, expressed in baculovirus infected Sf9 cells, ≥56% (SDS-PAGE)

Synonym(s):

phosphodiesterase 2A, cGMP-stimulated

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Assay:
≥56% (SDS-PAGE)
Biological source:
rat
Recombinant:
expressed in baculovirus infected Sf9 cells
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biological source

rat

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥56% (SDS-PAGE)

form

aqueous solution

mol wt

133 kDa

packaging

pkg of 5 μg

NCBI accession no.

NM_00143847

UniProt accession no.

Q01062

shipped in

dry ice

storage temp.

−70°C

Gene Information

rat ... PDE2A(81743)

General description

Rat PDE2A (GenBank Accession No. NM_00143847) full length with N-terminal His-GST-tag, MW=133 kDa, expressed in a Baculovirus infected Sf9 cell expression system

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Joachim Seybold et al.
Blood, 105(9), 3569-3576 (2005-01-15)
The pleiotropic cytokine tumor necrosis factor-alpha (TNF-alpha) and thrombin lead to increased endothelial permeability in sepsis. Numerous studies demonstrated the significance of intracellular cyclic nucleotides for the maintenance of endothelial barrier function. Actions of cyclic adenosine monophosphate (cAMP) and cyclic
Sergio E Martinez et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(20), 13260-13265 (2002-09-25)
Cyclic nucleotide phosphodiesterases (PDEs) regulate all pathways that use cGMP or cAMP as a second messenger. Five of the 11 PDE families have regulatory segments containing GAF domains, 3 of which are known to bind cGMP. In PDE2 binding of

Global Trade Item Number

SKUGTIN
SRP0428-5UG04061832782447