SAB5702486
[KO Validated]Anti-MLH1 Antibody, clone 8K1T2, Rabbit Monoclonal
Synonym(s):
COCA2, FCC2, HNPCC, HNPCC2, hMLH1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
8K1T2, monoclonal
form
liquid
mol wt
85 kDa
species reactivity
mouse, mouse
concentration
0.69 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200
western blot: 1:10000 - 1:68900
color
colorless
isotype
IgG
immunogen sequence
PGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGD
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MLH1(4292)
General description
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MLH1 (NP_000240.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
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