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MilliporeSigma

SAB1412596

Sigma-Aldrich

ANTI-SMAD4 antibody produced in mouse

clone 1G9, purified immunoglobulin, buffered aqueous solution

Synonym(s):

DPC4, JIP, MADH4, SMAD4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1G9, monoclonal

form

buffered aqueous solution

mol wt

antigen 36.63 kDa

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

NCBI accession no.

NM_005359

UniProt accession no.

Q13485

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SMAD4(4089)

Immunogen

SMAD4 (NP_005350, 421 a.a. ~ 520 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
APGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKE

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
06230-1G9
12174-S821

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Pasquale Piccolo et al.
European journal of human genetics : EJHG, 22(8), 988-994 (2014-01-09)
Myhre syndrome (MS, MIM 139210) is a connective tissue disorder that presents with short stature, short hands and feet, facial dysmorphic features, muscle hypertrophy, thickened skin, and deafness. Recurrent missense mutations in SMAD4 encoding for a transducer mediating transforming growth

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