RAB0674
Human CGB / Choriogonadotropin Subunit Beta ELISA Kit
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 40 pg/mL
standard curve range: 40.96-10000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CGB(1082)
General description
The antibody pair provided in this kit recognizes Human Chorionic Gonadotropin beta.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Chorionic gonadotropin β subunit 3 (CGB3), also referred as human chorionic gonadotropin- β (HCG-β) is a specific and active subunit, secreted by the syncytiotrophoblast of the placenta. It plays a vital role in embryo implantation. In addition, it acts like an agonist of luteinizing hormone (LH), stimulating progesterone secretion by the corpus luteum. Elevated expression of CGB3 enhance tumor invasion and is also used to predict poor prognosis of early-stage colorectal cancer (CRC).
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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Review: hCGs: different sources of production, different glycoforms and functions.
Fournier T, et al.
Placenta, 36(1), S60-S65 (2015)
B Subunit of Human Chorionic Gonadotropin Promotes Tumor Invasion and Predicts Poor Prognosis of Early-Stage Colorectal Cancer.
Li J, et al.
Cellular Physiology and Biochemistry, 45, 237-249 (2018)
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