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P6280

Pyridoxine hydrochloride

Name: Pyridoxine hydrochloride
Brand: SIGMA

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonym(s):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B₆ hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₁NO₃ · HCl

CAS Number:

58-56-0

Molecular Weight:

205.64

NACRES:

NA.21

PubChem Substance ID:

24898752

eCl@ss:

34058008

UNSPSC Code:

12161900

EC Number:

200-386-2

MDL number:

MFCD00012807

Beilstein/REAXYS Number:

3632435

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Properties

product line

BioReagent

assay

≥98% (HPLC)

form

powder

mol wt

M_w 205.64 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

mp

214-215 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

application(s)

agriculture

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Description

General description

Pyridoxine is a water-soluble vitamin that exists in six forms called, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate, and pyridoxal 5′-phosphate.

Application

Pyridoxine hydrochloride has been used:

as a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies
as a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA
as a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity

Biochem/physiol Actions

Pyridoxine functions as an essential coenzyme for amino acid, carbohydrate, and lipid metabolism. Pyridoxine deficiency is associated with peripheral neuropathy, microcytic anemia, and electroencephalographic abnormalities. It is implicated in a wide range of biochemical reactions that affect cellular processes. Pyridoxine serves as an alternative to pyridoxal which can degrade in media.

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pictograms

GHS05

signalword

Danger

hcodes

H318

pcodes

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

Vitamin B6's impact on serum-free cell culture systems is explored for protein manufacturing.

Uremic Toxin Lanthionine Interferes with the Transsulfuration Pathway, Angiogenetic Signaling and Increases Intracellular Calcium.

Carmela Vigorito et al.

International journal of molecular sciences, 20(9) (2019-05-11)

(1) The beneficial effects of hydrogen sulfide (H2S) on the cardiovascular and nervous system have recently been re-evaluated. It has been shown that lanthionine, a side product of H2S biosynthesis, previously used as a marker for H2S production, is dramatically

Activity of Pyrazinamide against Mycobacterium tuberculosis at Neutral pH in PZA-S1 Minimal Medium.

Wanliang Shi

Antibiotics (Basel, Switzerland), 10(8) (2021-08-28)

Susceptibility testing of tuberculosis (TB) drugs on Mycobacterium tuberculosis is essential for the rapid detection of strains resistant to the drugs, providing the patient with effective treatment, and preventing the spread of drug-resistant TB strains. Pyrazinamide (PZA) is one of

Bioassay to Study the Attachment of Xanthomonas albilineans on Sugarcane Leaves.

Imène Mensi et al.

Bio-protocol, 7(2), e2111-e2111 (2017-01-20)

Sugarcane (interspecific hybrids of Saccharum species) is an economically important crop that provides 70% of raw table sugar production worldwide and contributes, in some countries, to bioethanol and electricity production. Leaf scald, caused by the bacterial plant pathogen Xanthomonas albilineans

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Global Trade Item Number

SKU	GTIN
P6280-25G	04061834393245
P6280-100G	04061834393238
P6280-10G	04061835547944