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MilliporeSigma

P2918

Human Serum

from platelet poor human plasma, sterile-filtered, (mycoplasma tested, virus tested)

Synonym(s):

human plasma, human sera, human serum

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71
MDL number:
Biological source:
human
Origin:
USA origin
Sterility:
sterile-filtered
Shipped in:
dry ice
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biological source

human

sterility

sterile-filtered

origin

USA origin

technique(s)

cell culture | mammalian: suitable

impurities

(mycoplasma tested, virus tested), ≤10 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

General description

The serum is the fluid part of the blood containing plasma without fibrinogen.

Application

Human Serum has been used:
  • in the preparation of human serum samples that mimic the COVID-19 patient samples for serological antibody testing
  • as a media supplement to differentiate human induced pluripotent stem cells (hiPS) to hiPS- brain microvascular endothelial cells (BMEC)
  • for culturing transgenic Plasmodium falciparum clone
  • for assessing the electrochemical response of recombinant P. falciparum parasite L-lactate dehydrogenase (LDH) in serum samples
  • in platelet-derived growth factor (PDGF) purification assays

Human serum from platelet poor plasma (PPP) is useful for studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts. It has also been used in platelet derived growth factor (PDGF) purification assays.

Biochem/physiol Actions

Serum serves as a supplement to basal media formulations and conventional biomedical cell culture media. It acts as a source of trace nutrients, signaling molecules, growth factors, and hormones that induce proper cell growth in vitro. Human serum from platelet-poor plasma (PPP) is useful in the studies of the effects of platelet lysates on the growth of cells such as articular chondrocytes and human skin fibroblasts.

Analysis Note

Endotoxin tested

Other Notes

It is not unusual for a white precipitate to form following a freeze-thaw cycle for this human serum product.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.


Y C Choi et al.
Arthritis and rheumatism, 23(2), 220-224 (1980-02-01)
Human platelet lysate (PL) has a strong growth promoting action on rabbit articular chondrocytes in monolayer culture. The responsible factor is heat stable (56 degrees C, 30 minutes) and above 10,000 MW. PL (80 microgram protein/ml) reduces cell protein content
Y Umeno et al.
Journal of cell science, 94 ( Pt 3), 567-575 (1989-11-01)
We examined the proliferative behaviour in tertiary culture cells of human skin fibroblasts (HSF) as well as cells of the rat 3Y1 diploid fibroblast line placed on a plastic substratum in a nutrient-rich medium containing high concentrations of platelet-poor plasma
Physiology, Blood Plasma null



Global Trade Item Number

SKUGTIN
P2918-20ML04061834365839
P2918-100ML04061834365822