M2393
Magnesium chloride hexahydrate
BioReagent, suitable for cell culture, suitable for insect cell culture
Synonym(s):
MgCl2 hexahydrate, MgCl2.6H2O
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About This Item
Linear Formula:
MgCl2 · 6H2O
CAS Number:
Molecular Weight:
203.30
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.71
Solubility:
H2O: soluble 500 mg/mL, clear, colorless
product line
BioReagent
Quality Level
technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
solubility
H2O: soluble 500 mg/mL, clear, colorless
SMILES string
O.O.O.O.O.O.Cl[Mg]Cl
InChI
1S/2ClH.Mg.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2
InChI key
DHRRIBDTHFBPNG-UHFFFAOYSA-L
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Application
Magnesium chloride hexahydrate (MgCl2·6H2O) has been used:
- to prepare electrochemical substrate solution for surface treatment and immunoassay preparation of monoclonal anti-creatine kinase (CK-MB) antibody
- as a component of casamino acids medium (Hv-Ca) to culture Haloferax volcanii strains
- to prepare hydrated-salt poly(vinylidenefluoride)-hexafluoropropylene P(VDF-HFP)/MgCl2·6H2O nanocomposite film to study its phase transformation, surface morphology and dielectric property
Biochem/physiol Actions
Magnesium chloride is commonly used as a reagent in chemistry and molecular biology as a source of magnesium ions. Magnesium exhibits several biological roles in enzymology, cell membrane and wall structural integrity, muscle cell physiology, and nucleic acid structure. It functions as a co-factor in various enzymes, like deoxyribonuclease (DNAse), the restriction enzymes EcoRI and EcoRV, and Ribonuclease H. Magnesium stabilizes polymeric nucleic acids including ribozymes and transfer RNA.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Roshali T de Silva et al.
Microbiology (Reading, England), 167(2) (2021-01-19)
Some microbes display pleomorphism, showing variable cell shapes in a single culture, whereas others differentiate to adapt to changed environmental conditions. The pleomorphic archaeon Haloferax volcanii commonly forms discoid-shaped ('plate') cells in culture, but may also be present as rods
Christopher D L Johnson et al.
ACS applied materials & interfaces, 11(1), 356-372 (2018-12-06)
Magnetic electrospun fibers are of interest for minimally invasive biomaterial applications that also strive to provide cell guidance. Magnetic electrospun fibers can be injected and then magnetically positioned in situ, and the aligned fiber scaffolds provide consistent topographical guidance to
Vladimir Riazanski et al.
iScience, 23(11), 101759-101759 (2020-12-01)
The relative contribution of the two phagosomal catabolic processes, oxidative and metabolic, was assessed in the killing of Pseudomonas aeruginosa in phagosomes of alveolar macrophages (AMs) from wild-type (p47-phox +/+ ) or NOX-defective (p47-phox -/- ) mice. Free radical release
Liang Yang et al.
International journal of pharmaceutics, 471(1-2), 258-263 (2014-05-20)
Telmisartan (TEL) belongs to BCS class II (low solubility/high permeability) and exhibits the pH-dependent drug release. Since 3-aminopropyl functionalized magnesium phyllosilicate (aminoclay) can intercalate or adsorb the negatively charged molecules via the electrostatic interaction, TEL-aminoclay complex was synthesized to improve
Xingchu Gong et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 93, 260-266 (2015-04-25)
Brittleness is one of the important material properties that influences the success or failure of powder compaction. We have discovered that the reciprocal of diametrical elastic strain at fracture is the most suitable tablet brittleness indices (TBIs) for quantifying brittleness
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