L8039
Lipoprotein, high density from human plasma
≥95% (SDS-PAGE), solution
Synonym(s):
α-Lipoprotein, HDL, High density lipoprotein
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About This Item
biological source
human plasma
Quality Level
assay
≥95% (SDS-PAGE)
form
solution
packaging
vial of 10 mg protein
technique(s)
cell culture | mammalian: suitable
functional group
ester, phospholipid
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... APOB(338), APOC2(344), APOE(348)
Biochem/physiol Actions
High density lipoprotein (HDL) serves as the transit agent for cholesterol away from blood, tissues, and organs of the body to the liver, where cholesterol breakdown occurs. This process ultimately helps to remove cholesterol from the arteries. Colloquially known as the "good cholesterol", HDL makes up 20%-30% of the total cholesterol in the body.
HDL is used in cardiovascular research and the development of potential therapeutic approaches to cardiovascular risk management.
HDL is used in cardiovascular research and the development of potential therapeutic approaches to cardiovascular risk management.
Physical form
Solution in 150 mM NaCl and 0.01% EDTA, pH 7.4.
Other Notes
View more information on lipoprotein function and lipid transport at www.sigma-aldrich.com/enzymeexplorer
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Articles
Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.
Tisha R Joy
Pharmacology & therapeutics, 135(1), 18-30 (2012-04-03)
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has been associated with a 25-30% reduction in cardiovascular disease risk. However, there still remains a significant and quantifiable risk. Since epidemiologic data have demonstrated that low levels of high-density lipoprotein cholesterol (HDL-C)
Kyung-Hyun Cho
Medicines (Basel, Switzerland), 8(7) (2021-08-07)
The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I
Mark J Cziraky et al.
Journal of managed care pharmacy : JMCP, 14(8 Suppl), S3-28 (2009-11-07)
Most clinicians recognize the importance of reducing low-density lipoprotein cholesterol (LDL-C) and, therefore, address this therapeutic need to decrease cardiovascular disease risk. In addition to the critical role that LDL-C plays, recent studies have shown the contribution of other lipid
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L8039-10MG | 04061833965870 |