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I0898

Sigma-Aldrich

D-Ile-Pro-Arg p-nitroanilide dihydrochloride

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C23H36N8O5 · 2HCl
CAS Number:
96323-41-0
Molecular Weight:
577.50
MDL number:
MFCD00792772
UNSPSC Code:
12352204
PubChem Substance ID:
329815329
NACRES:
NA.83

Key Documents

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Quality Level

200

assay

≥95% (HPLC)

form

powder

solubility

water: 1 mg/mL, clear, colorless to faintly yellow

SMILES string

Cl.Cl.CC[C@@H](C)[C@@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc2ccc(cc2)[N+]([O-])=O

InChI

1S/C23H36N8O5.2ClH/c1-3-14(2)19(24)22(34)30-13-5-7-18(30)21(33)29-17(6-4-12-27-23(25)26)20(32)28-15-8-10-16(11-9-15)31(35)36;;/h8-11,14,17-19H,3-7,12-13,24H2,1-2H3,(H,28,32)(H,29,33)(H4,25,26,27);2*1H/t14-,17+,18+,19-;;/m1../s1

InChI key

NAANFMDBMZZFRD-CYTOJJGESA-N

General description

Chromogenic substrate for tissue plasminogen activator (t-PA).

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SLCD2871
SLCC8367
SLCC3812
SLCC2330
SLCB2562

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Verheijen, J.H., et al. et al.
Methods of Enzymatic Analysis, 5, 425-425 (1984)
Jorge Frias et al.
Journal of microbiology and biotechnology, 31(2), 327-337 (2020-11-06)
Fibrinolytic enzymes with a direct mechanism of action and safer properties are currently requested for thrombolytic therapy. This paper reports on a new enzyme capable of degrading blood clots directly without impairing blood coagulation. This enzyme is also non-cytotoxic and

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