Skip to Content
MilliporeSigma

I0658

Sigma-Aldrich

IC 261

≥98% (HPLC)

Synonym(s):

1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one, SU5607

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C18H17NO4
CAS Number:
186611-52-9
Molecular Weight:
311.33
MDL number:
MFCD00118156
UNSPSC Code:
12352200
PubChem Substance ID:
24278111
NACRES:
NA.77

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

yellow

solubility

DMSO: >10 mg/mL

SMILES string

COc1cc(OC)c(\C=C2/C(=O)Nc3ccccc23)c(OC)c1

InChI

1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10-

InChI key

JBJYTZXCZDNOJW-RAXLEYEMSA-N

Gene Information

human ... CSNK1D(1453), CSNK1E(1454)

Related Categories

Biochem/physiol Actions

Casein kinase 1 δ (CK1δ) and CK1 ε inhibitor.

Physical form

Product is a mixture of the Z- and E-isomers, with the predominant isomer expected to be E.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
100M4624V
100M4624
108K4606
013K4622

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Marta Vázquez-Cedeira et al.
PloS one, 6(8), e23235-e23235 (2011-08-11)
Human vaccinia-related kinases (VRK1 and VRK2) are atypical active Ser-Thr kinases implicated in control of cell cycle entry, apoptosis and autophagy, and affect signalling by mitogen activated protein kinases (MAPK). The specific structural differences in VRK catalytic sites make them
Konstantinos Gkatzis et al.
eLife, 10 (2021-09-30)
Lung epithelial progenitors differentiate into alveolar type 1 (AT1) and type 2 (AT2) cells. These cells form the air-blood interface and secrete surfactant, respectively, and are essential for lung maturation and function. Current protocols to derive and culture alveolar cells

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service