C4980
Anti-Calcium Channel (Cardiac α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB CL
Citations:
7
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
rabbit, rat
technique(s)
immunoprecipitation (IP): suitable, western blot (chemiluminescent): suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Cacna1c(24239)
Immunogen
N-terminal residues 1-46 of rabbit cardiac type α1C subunit fused to GST.
Physical form
Lyophilized from PBS, pH 7.4, containing 1% BSA, and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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E Shistik et al.
The Journal of biological chemistry, 274(44), 31145-31149 (1999-10-26)
The first 46 amino acids (aa) of the N terminus of the rabbit heart (RH) L-type cardiac Ca(2+) channel alpha(1C) subunit are crucial for the stimulating action of protein kinase C (PKC) and also hinder channel gating (Shistik, E., Ivanina
A Mikami et al.
Nature, 340(6230), 230-233 (1989-07-20)
In cardiac muscle, where Ca2+ influx across the sarcolemma is essential for contraction, the dihydropyridine (DHP)-sensitive L-type calcium channel represents the major entry pathway of extracellular Ca2+. We have previously elucidated the primary structure of the rabbit skeletal muscle DHP
Bruno Barcellos Jacobsen et al.
Arquivos brasileiros de cardiologia, 109(5), 432-439 (2017-10-27)
Different types of high-fat and/or high-energy diets have been used to induce obesity in rodents. However, few studies have reported on the effects observed at the initial stage of obesity induced by high-fat feeding on cardiac functional and structural remodelling.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C4980-.2ML | 04061838172204 |
| C4980-.05ML | 04061838172198 |