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A8751

Sigma-Aldrich

Adenine hydrochloride hydrate

≥99%, powder

Synonym(s):

Adenine hydrochloride, Adenine,monohydrochloride, 6-Aminopurine hydrochloride hydrate

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About This Item

Empirical Formula (Hill Notation):
C5H5N5 · HCl · xH2O
CAS Number:
2922-28-3
Molecular Weight:
171.59 (anhydrous basis)
MDL number:
MFCD00150864
UNSPSC Code:
41106305
PubChem Substance ID:
24891361
NACRES:
NA.51

Key Documents

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Product Name

Adenine hydrochloride hydrate, ≥99%

biological source

synthetic

Quality Level

200

assay

≥99%

form

powder

solubility

warm water: 50 mg/mL, clear to hazy, colorless to faint yellow or tan

SMILES string

O.Cl.Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5.ClH.H2O/c6-4-3-5(9-1-7-3)10-2-8-4;;/h1-2H,(H3,6,7,8,9,10);1H;1H2

InChI key

MYRDTAUFFBYTHA-UHFFFAOYSA-N

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General description

Adenine is a purine nucleobase with a wide range of chemical and biochemical roles in vivo and in vitro. It is a regulatory molecule and a component of DNA, RNA, cofactors (NAD, FAD), and signaling molecules (cAMP).

Application

Adenine hydrochloride hydrate has been used:

  • as a supplement in a rich medium for galactose induction during yeast cell culture.
  • for the incubation of MiaPaCa2 cell lines for cell viability and co-culture assay.
  • as a component of the Pombe Glutamate (PMG)media for the germination of Schizosaccharomyces pombe.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ3761
SLCH7410
SLCF6256
SLCD0489
SLCB9820

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Isabelle Loïodice et al.
Cells, 10(11) (2021-11-28)
In eukaryotic cells, silent chromatin is mainly found at the nuclear periphery forming subnuclear compartments that favor silencing establishment. Here, we set up an inducible system to monitor silencing establishment at an ectopic locus in relation with its subnuclear localization

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