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A5880

Sigma-Aldrich

D-Amphetamine hemisulfate salt

Synonym(s):

(+)-α-Methylphenethylamine hemisulfate salt, Dextroamphetamine hemisulfate salt

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About This Item

Empirical Formula (Hill Notation):
C9H13N · 0.5 H2SO4
CAS Number:
51-63-8
Molecular Weight:
184.25
EC Number:
200-111-6
MDL number:
MFCD00069209
UNSPSC Code:
12352116
PubChem Substance ID:
24891028
NACRES:
NA.77

Key Documents

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form

powder

Quality Level

200

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
kontrollierte Droge in Deutschland

solubility

H2O: soluble
ethanol: soluble

application(s)

forensics and toxicology

SMILES string

OS(O)(=O)=O.CC(N)Cc1ccccc1.CC(N)Cc2ccccc2

InChI

1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)/t2*8-;/m00./s1

InChI key

PYHRZPFZZDCOPH-QXGOIDDHSA-N

Gene Information

human ... SLC18A2(6571)

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Application

D-Amphetamine hemisulfate salt has been used in oxidative fermentative (OF) test, and exploratory test.

Biochem/physiol Actions

D-Amphetamine is an active isomer of amphetamine. It induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites, which blocks catecholamine reuptake.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ8611
SLCB1164
SLBX4973
SLBS5062
SLBQ9119V

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J Cartmell et al.
The Journal of pharmacology and experimental therapeutics, 291(1), 161-170 (1999-09-22)
Previous animal studies have indicated that drugs targeted at metabotropic glutamate (mGlu) receptors may be useful for treatment of psychosis. In this article, the effects of the novel, potent, and selective mGlu2/3 receptor agonists LY354740 and LY379268, and the clinically
Timothy J O'Neal et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 45(8), 1251-1262 (2019-11-21)
Opioid addiction has been declared a public health emergency, with fatal overdoses following relapse reaching epidemic proportions and disease-associated costs continuing to escalate. Relapse is often triggered by re-exposure to drug-associated cues, and though the neural substrates responsible for relapse
A M Barr et al.
Pharmacology, biochemistry, and behavior, 64(3), 597-604 (1999-11-05)
The present study sought to determine the effect of withdrawal from an escalating dose schedule of d-amphetamine on sexual behavior in male rats. Tests were conducted every 5 days until stable levels of sexual behavior were obtained. With repeated testing
Cedric Jackson et al.
Behavioural brain research, 361, 131-138 (2018-12-15)
Although scientific research using mammalian models has made great strides in uncovering the enigmatic neural and molecular mechanisms orchestrating the state of drug addiction, a complete understanding has thus far eluded researchers. The complexity of the task has led to
Antonio Alcaro et al.
Pharmacology, biochemistry, and behavior, 99(1), 75-80 (2011-04-21)
In mammals, rewarding properties of drugs depend on their capacity to activate a dopamine-mediated appetitive motivational seeking state--a system that allows animals to pursue and find all kinds of objects and events needed for survival. With such states strongly conserved
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